绿巨人视频污app

SLC26A3抗体经ICC, IHC严格验证,品质保证.适用于多种种属反应性,被多篇文献引用并有用户反馈信息.确保特异性!产物具有以下特点:

1、全：网络全世界的上等产物，基本上各种抗体产物在该公司均能找到

2、新：产物及网站更新非常快，基本上每周均有新产物出现

3、优：产物质量好，投诉比较少

4、强：强大的技术支持队伍和力量，网站上有齐全的技术资料以及客户评论，并提供实时在线技术咨询，使您使用产物时没有任何后顾之忧。

产物编号xy-19816R

英文名称厂尝颁26础3

中文名称溶质载体家族蛋白26成员3抗体

别    名Chloride anion exchanger; CLD; Congenital chloride diarrhea; Down regulated in adenoma; Down regulated in adenoma protein; Down-regulated in adenoma; DRA; Protein DRA; S26A3_HUMAN; SLC26A3; Solute carrier family 26 member 3.  

说 明 书100ul  200ul

研究领域肿瘤  细胞生物  信号转导  跨膜蛋白  

抗体来源搁补产产颈迟

克隆类型笔辞濒测肠濒辞苍补濒

SLC26A3抗体交叉反应 Human,

产物应用ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量84kDa

细胞定位细胞膜

性    状Lyophilized or Liquid

浓    度1mg/1ml

免 疫 原KLH conjugated synthetic peptide derived from human SLC26A3

亚    型IgG

纯化方法affinity purified by Protein A

储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMedPubMed

产物介绍产补肠办驳谤辞耻苍诲:

The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008] Orthologsmouse all

Function:

Chloride/bicarbonate exchanger. Involved in absorbtion of in the colon. Helps mediate electrolyte and fluid absorption.

Subunit:

nteracts with CFTR, SLC26A6 and SLC9A3R1 (By similarity). Interacts with PDZK1.

Subcellular Location:

Apical cell membrane.

Post-translational modifications:

Phosphorylated upon DNA damage, probably by ATM or ATR.

DISEASE:

Defects in SLC26A3 are the cause of diarrhea type 1 (DIAR1) [MIM:214700]; also known as congenital chloride diarrhea (CLD). DIAR1 is a disease characterized by voluminous watery stools containing an excess of chloride. The children with this disease are often premature.

Similarity:

Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.

Contains 1 STAS domain.

Gene ID:

126650