染色体脆弱性相关基因抗体
规格:1尘驳/1尘濒
英文名: ATAD5
别名: ATPase family AAA domain containing 5; C17orf41; chromosome fragility associated gene 1; FRAG1; Putative uncharacterized protein Fragment.
分子量: 203kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ATAD5
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,
细胞定位:细胞核
染色体脆弱性相关基因抗体产物介绍:background: ATAD5 is a homolog of a subunit of RFC (replication factor C) and has been shown to be down-regulated in response to replicative stress. ATAD5 may play a role in the surveillance of DNA damage and the cell’s decision to survive or activate apoptosis. Subunit: "Interacts with RB1 predominantly in G1 phase via its LXCXE motif.染色体脆弱性相关基因抗体 Interacts with RAD9A in growing cells. The interaction with RAD9A is reduced after exposure to DNA replication-inhibiting agents. Subcellular Location: Nucleus. Similarity: Belongs to the AAA ATPase family. Important Note: This product as supplied is intended染色体脆弱性相关基因抗体 for research use only, not for use in human, therapeutic or diagnostic applications.
染色体脆弱性相关基因抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 染色质和核信号 细胞凋亡 细胞周期蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid