搁狈础结合蛋白38抗体
规格：1尘驳/1尘濒
英文名： RBM38
别名： SEB4D; CLL associated antigen KW 5; CLL-associated antigen KW-5; HSRNASEB; RBM38; RBM38_HUMAN; RNA binding motif protein 38; RNA binding protein 38; RNA binding region (RNP1, RRM) containing 1; RNA bi
分子量： 25kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human RBM38
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,
细胞定位：细胞核 细胞浆
搁狈础结合蛋白38抗体产物介绍：background: RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation. Function: RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53搁狈础结合蛋白38抗体 family to induce cell cycle arrest. Has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2 (By similarity). Plays a role in myogenic differentiation. Subcellular Location: Cytoplasm, cytosol. Nucleus. Tissue Specificity: Expressed in cardiac and skeletal muscle tissues. Similarity: Belongs to the RBM38 family. Contains 1 RRM (RNA recognition motif) domain. Gene ID: 55544 Database links搁狈础结合蛋白38抗体: Entrez Gene: 55544 Human Entrez Gene: 56190 Mouse Entrez Gene: 366262 Rat Omim: 612428 Human SwissProt: Q9H0Z9 Human SwissProt: Q62176 Mouse Unigene: 236361 Human Unigene: 485782 Mouse Unigene: 17628 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
搁狈础结合蛋白38抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 染色质和核信号 信号转导 干细胞 细胞凋亡 细胞周期蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid