卷曲螺旋结构域蛋白8抗体
规格：1尘驳/1尘濒
英文名： CCDC8
别名： CCDC8; CCDC8_HUMAN; Coiled-coil domain-containing protein 8; DKFZp564K0322; ENSMUSG00000041117; MGC72567.
分子量： 59kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CCDC8
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse,
细胞定位：
卷曲螺旋结构域蛋白8抗体产物介绍：background: This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3). [provided by RefSeq, Dec 2011]. Subunit: Interacts with OBSL1. Tissue Specificity: Widely expressed with low levels in spleen, skeletal muscle, small intestine,卷曲螺旋结构域蛋白8抗体 kidney and liver. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. DISEASE: Defects in CCDC8 are the cause of 3M syndrome type 3 (3M3) [MIM:614205]. A disorder characterized by poor postnatal growth and distinctive facial features, including triangular facies, frontal bossing, fleshy tipped nose, and fleshy lips. Other features may include skeletal anomalies and prominent heels. Database links: UniProtKB/Swiss-Prot: Q9H0W5.2 Important Note: This product as supplied is intended for research use only, 卷曲螺旋结构域蛋白8抗体not for use in human, therapeutic or diagnostic applications.
卷曲螺旋结构域蛋白8抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid