转导β样蛋白1抗体
规格:1尘驳/1尘濒
英文名: TBL1Y
别名: Y-linked; F-box-like/WD repeat-containing protein TBL1Y; TBL1; TBL1Y; TBL1Y_HUMAN; Transducin (beta) like 1, Y linked; Transducin beta-like 1; Transducin beta-like protein 1Y; Transducin-beta-like pro
分子量: 57kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from huamn TBL1Y
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:细胞核
转导β样蛋白1抗体产物介绍:background: FunctionF-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange. Function: F-box-like protein involved in the recruitment of theubiquitin/19S proteasome complex to nuclear receptor-regulatedtranscription units. Plays an essential role in transcriptionactivation mediated by nuclear receptors. Probably acts as integralcomponent of corepressor complexes that mediates the recruitment转导β样蛋白1抗体 ofthe 19S proteasome complex, leading to the subsequent proteasomaldegradation of transcription repressor complexes, thereby allowingcofactor exchange (By similarity). Subunit: Probable component of the N-Cor repressor complex andsome E3 ubiquitin ligase complex (By similarity). Subcellular Location: Nucleus (By similarity). Tissue Specificity: Fetal brain and prostate. Similarity: Belongs to the WD r转导β样蛋白1抗体epeat EBI family. Contains 1 F-box-like domain. Contains 1 LisH domain. Contains 8 WD repeats. Database links: UniProtKB/Swiss-Prot: Q9BQ87.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转导β样蛋白1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 染色质和核信号 信号转导 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid