贵础惭129叠蛋白抗体
规格：1尘驳/1尘濒
英文名： FAM129B
别名： chromosome 9 open reading frame 88; DKFZP434H0820; FAM129B; family with sequence similarity 129, member B; FLJ13518; FLJ22151; FLJ22298; hypothetical protein LOC64855; Meg 3; Meg-3; Meg3; Niban like p
分子量： 83kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FAM129B
交叉反应：Human, Mouse, Rat, Dog, Cow, Sheep,
细胞定位：细胞浆 细胞膜
贵础惭129叠蛋白抗体产物介绍：background: May play a role in apoptosis suppression. May promote melanoma cell invasion in vitro. Subcellular Location: Cytoplasm, cytosol. Cell junction, adherens junction. Note=In exponentially growing cells, exclusively cytoplasmic. Cell membrane localization is observed when cells reach confluency and during telophase. In melanoma cells, targeting to the plasma membrane may be impaired by C-terminal phosphorylation. Post-translational modifications: Phosphorylated at Ser-641, Ser-646, Ser-692 and Ser-696 by the BRAF/MKK/ERK signaling cascade. In melanoma cells, the C-terminal phosphorylation may prevent targeting to the plasma membrane. As贵础惭129叠蛋白抗体 apoptosis proceeds, degraded via an proteasome-independent pathway, probably by caspases (PubMed:21148485). Similarity: Belongs to the Niban family. Contains 1 PH domain. Gene ID: 64855 Database links: Entrez Gene: 64855 Human Entrez 贵础惭129叠蛋白抗体Gene: 227737 Mouse SwissProt: Q96TA1 Human SwissProt: Q8R1F1 Mouse Unigene: 522401 Human Unigene: 301646 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
贵础惭129叠蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid