蛋白磷酸酶1调节亚基15叠抗体
规格:1尘驳/1尘濒
英文名: PPP1R15B
别名: CREP; FLJ14744; PPP1R15B; Protein phosphatase 1, regulatory (inhibitor) subunit 15B; Protein phosphatase 1, regulatory subunit 15B.
分子量: 79kDa
储存液:Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PPP1R15B
交叉反应:Human, Mouse, Rat, Cow, Rabbit, Sheep,
细胞定位:细胞浆
蛋白磷酸酶1调节亚基15叠抗体产物介绍:background: PPP1R15B belongs to the PPP1R15 family. It maintains low levels of EIF2S1 phosphorylation in un-stressed cells by promoting its dephosphorylation by PP1. The phosphatase activity of the PPP1R15B-PP1 complex toward EIF2S1 is specifically inhibited by Salubrinal, a drug that protects cells from endoplasmic reticulum stress. Function: Maintains low levels of EIF2S1 phosphorylation in unstressed cells by promoting its dephosphorylation by PP1 Subunit: PPP1R15B promotes dephosphorylation 蛋白磷酸酶1调节亚基15叠抗体of the transcription initiation factor EIF2-alpha (EIF2S1; MIM 603907) through recruitment of protein phosphatase-1 (PP1) catalytic subunits. Similarity: Belongs to the PPP1R15 family. Gene ID: 84919 Database links: Entrez Gene: 84919 Human Entrez Gene:蛋白磷酸酶1调节亚基15叠抗体 108954 Mouse Entrez Gene: 304799 Rat Omim: 613257 Human SwissProt: Q5SWA1 Human SwissProt: Q8BFW3 Mouse Unigene: 304376 Human Unigene: 293628 Mouse Unigene: 78049 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
蛋白磷酸酶1调节亚基15叠抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid