吡哆醛激酶抗体
规格:1尘驳/1尘濒
英文名: PDXK
别名: PDXK.1; pdxK; PDXK_HUMAN; PKH; PNK; Pyridoxal kinase; Pyridoxamine kinase; Pyridoxine kinase; Vitamin B6 kinase.
分子量: 35kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PDXK
交叉反应:Human, Mouse, Rat, Dog, Horse,
细胞定位:细胞浆
吡哆醛激酶抗体产物介绍:background: Pyridoxal kinase belongs to the pyridoxine kinase family and phosphorylates vitamin B6, a step necessary for the conversion of vitamin B6 to pyridoxal 5’ phosphate (PLP), the active form of vitamin B6. PLP acts as a coenzyme and functions to maintain homeostasis. Pyridoxal kinase is a 312-amino acid cytoplasmic protein that may act as a homodimer and is expressed ubiquitously. There are three known isoforms of pyridoxal kinase, and isoform 3 expression is observed in testis and spermatozoa. The optimum pH for pyridoxal kinase is between 5.5 and 6.0. PDXK, the gene that encodes the pyridoxal kinase protein, maps to chromosome 21q22.3 吡哆醛激酶抗体and may be a candidate gene for autoimmune polyglandular disease type 1, a genetic disorder that has been mapped to the same region on chromosome 21. Function: Required for synthesis of pyridoxal-5-phosphate from vitamin B6. Subunit: Homodimer (Probable). Subcellular Location: Cytoplasm Tissue Specificity: Ubiquitous. Isoform 3 is detected in testis and spermatozoa. Similarity: Belongs to the pyridoxine kinase family. Database links: Entrez Gene: 8566 Human Entrez Gene: 216134 Mouse Omim: 179020 Human SwissProt: O00764吡哆醛激酶抗体 Human SwissProt: Q8K183 Mouse Unigene: 284491 Human Unigene: 206159 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
吡哆醛激酶抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid