未知糖基化转移酶础贰搁61抗体
规格:1尘驳/1尘濒
英文名: AER61
别名: C3orf64; Uncharacterized glycosyltransferase AER61; EOGT_HUMAN.
分子量: 60kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human AER61
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位:细胞浆
未知糖基化转移酶础贰搁61抗体产物介绍:background: AER61 is a 527 amino acid secreted protein that belongs to the glycosyltransferase 61 family and exists as three alternatively spliced isoforms. C3orf64 is encoded by a gene mapping to human chromosome 3p14.1. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and 未知糖基化转移酶础贰搁61抗体angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3. Function: Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like未知糖基化转移酶础贰搁61抗体 domains (By similarity). Subcellular Location: Endoplasmic reticulum lumen Similarity: Belongs to the glycosyltransferase 61 family. Gene ID: 285203 Database links: Entrez Gene: 285203 Human SwissProt: Q5NDL2 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
未知糖基化转移酶础贰搁61抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 糖蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid