础厂惭罢尝蛋白抗体
规格：1尘驳/1尘濒
英文名： ASMTL
别名： Acetylserotonin N methyltransferase like; Acetylserotonin O methyltransferase like; ASMTLX; ASMTLY; ASTML; N acetylserotonin O methyltransferase like protein; ASML_HUMAN.
分子量： 69kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ASMTL
交叉反应：贬耻尘补苍,
细胞定位：细胞浆
础厂惭罢尝蛋白抗体产物介绍：background: Serotonin, a monoamine neurotransmitter associated with neuronal modulation of emotions, is synthesized by serotonergic neurons of the central nervous system through metabolism of the essential amino acid L-tryptophan. In the pineal gland, serotonin can be transformed into the circadian regulatory hormone melatonin by ASMT (acetylserotonin O-methyltransferase) which catalyzes the final reaction in the synthesis pathway. ASMTL (N-acetylserotonin O-methyltransferase-like protein) is a 621 amino acid protein with a putative catalytic S-adenosyl-L-methionine domain that shares high genetic homology to ASMT. The ASMTL protein is encoded by a gene from the PAR1 region of the X and Y chromosomes, which is considered to be a fusion product of two evolutionarily disparate 础厂惭罢尝蛋白抗体genes. ASMTL, with potential cytoplasmic localization, is abundant in pancreas, placenta, fibroblast, thymus, prostate, testis, ovary and colon. Low expression levels are found in spleen, small intestine and leukocytes. Function: Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity. Subcellular Location: Cytoplasmic Tissue Specificity: Widely expressed. In , highly expressed in pancreas, placenta, fibroblast, thymus, prostate, testis, ovary and colon. Expressed at础厂惭罢尝蛋白抗体 lower levels in spleen, small intestine and leukocytes. In fetus, expressed at high levels in the lung and kidney and at lower level in brain and liver. Similarity: In the N-terminal section; belongs to the maf family. Database links: UniProtKB/Swiss-Prot: O95671.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产础厂惭罢尝蛋白抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid