转录辅助因子退变样蛋白4抗体
规格：1尘驳/1尘濒
英文名： VGLL4
别名： Transcription cofactor vestigial like protein 4; Vestigial like protein 4; VGL 4; VGLL4; VGLL4_HUMAN.
分子量： 31kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human VGLL4
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
转录辅助因子退变样蛋白4抗体产物介绍：background: The transcriptional enhancer factor-1 (TEF-1) family of transcription factors regulate tissue-specific gene expression in muscle and placenta. The mechanism whereby TEF-1 confers tissue specificity depends largely on the interaction of TEF-1 with tissue-specific cofactors. Transcription cofactor Vgl-4 (vestigial-like protein 4) is a 290 amino acid nuclear protein that interacts with TEF-1 and MEF-2. Vgl-4 is the only member of the vestigial-like family that is expressed in heart. Overexpression of Vgl-4 in cardiac myocytes interferes with basal expression and ?-adrenergic receptor-dependent activation of a TEF-1 dependent skeletal ?actin promoter. 转录辅助因子退变样蛋白4抗体This suggests that Vgl-4 counteracts ?-adrenergic activation of gene expression in cardiomyocytes. There are two isoforms of Vgl-4 that are produced as a result of alternative splicing events. Function: May act as a specific coactivator for the mammalian TEFs (By similarity). Subunit: Interacts with TEFs (By similarity). Interacts with IRF2BP2. Subcellular Location: Nuclear Similarity: Belongs to the 转录辅助因子退变样蛋白4抗体vestigial family. Gene ID: 9686 Database links: Entrez Gene: 9686 Human Entrez Gene: 232334 Mouse Entrez Gene: 297523 Rat SwissProt: Q14135 Human SwissProt: Q80V24 Mouse Unigene: 23131 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录辅助因子退变样蛋白4抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid