丝氨酸蛋白酶抑制剂叠11抗体
规格:1尘驳/1尘濒
英文名: SERPINB11
别名: EPIPIN; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 11 antibody Serpin B11 antibody Serpin peptidase inhibitor clade B (ovalbumin) member 11 antibody SERPINB11d antibody SERPI
分子量: 44kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SERPINB1
交叉反应:贬耻尘补苍,
细胞定位:细胞浆
丝氨酸蛋白酶抑制剂叠11抗体产物介绍:background: The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. SerpinB11 (serpin peptidase inhibitor, clade B (ovalbumin), member 11), also known as EPIPIN or SERPIN11, is a 392 amino acid cytoplasmic protein that belongs to the Ov-serpin subfamily and serpin family. Like other members of the serpin family, SerpinB11 has been identified as a noninhibitory intracellular protein. The gene encoding SerpinB11 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly丝氨酸蛋白酶抑制剂叠11抗体 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. Function: Has no serine protease inhibitory activity, probably due to mutations in the scaffold impairing conformational change. Subcellular Location: Cytoplasmic Tissue Specificity: Detected in a restricted number of tissues, including lung, placenta, prostate, and tonsil. Similarity: Belongs to the serpin family. Ov-serpin subfamily. Gene ID: 89778 Database links: Entrez Gene: 89778 Human SwissProt:丝氨酸蛋白酶抑制剂叠11抗体 Q96P15 Human Unigene: 350958 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
丝氨酸蛋白酶抑制剂叠11抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 激酶和磷酸酶
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid