贵滨骋狈尝1蛋白抗体
规格:1尘驳/1尘濒
英文名: FIGNL1
别名: Fidgetin like protein 1; fidgetin-like 1; FIGL1_HUMAN.
分子量: 74kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FIGNL1
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep,
细胞定位:
贵滨骋狈尝1蛋白抗体产物介绍:background: FIGNL1 is a 674 amino acid protein belonging to the AAA ATPase family. FIGNL1 exists as a hexamer that undergoes alternative splicing to produce two isoforms. FIGNL1 utilizes magnesium as a cofactor and is phosphorylated upon DNA damage, probably by ATM or ATR. FIGNL1 is suggested to regulate osteoblast proliferation and differentiation. FIGNL1 is encoded by a gene located on human chromosome 7, which consists about 158 milllion bases, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by贵滨骋狈尝1蛋白抗体 mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. Function: May regulate osteoblast proliferation and differentiation (By similarity). Subunit: Hexamer (By similarity). Similarity: 贵滨骋狈尝1蛋白抗体Belongs to the AAA ATPase family. Database links: Entrez Gene: 63979 Human Entrez Gene: 63979 Mouse SwissProt: Q6PIW4 Human SwissProt: Q8BPY9 Mouse Unigene: 137516 Human Unigene: 236114 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产贵滨骋狈尝1蛋白抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 发育生物学 神经生物学 信号转导 细胞周期蛋白 细胞分化 细胞骨架 细胞外基质
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid