活化罢细胞核因子5蛋白抗体
规格：1尘驳/1尘濒
英文名： NFAT5
别名： Glutamine rich protein H65; KIAA0827; NF AT5; NF-AT5; NFAT 5; NFAT L1; NFAT like protein 1; NFAT5; NFAT5_HUMAN; NFATL 1; NFATL1; NFATZ; Nuclear factor of activated T cells 5; Nuclear factor of activat
分子量： 166kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NFAT5
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
活化罢细胞核因子5蛋白抗体产物介绍：background: The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. Function: Plays a role in the inducible expression of genes. Regulates hypertonicity-induced cellular accumulation of osmolytes. Subunit: Homodimer when bound to DNA, completely encircles its DNA target. Does not bind with Fos and Jun transcription factors. Subcellular Location: Nucleus. Tissue Specificity: Highest levels in skeletal muscle, brain, heart and peripheral blood leukocytes. Also expressed in placenta, lung,活化罢细胞核因子5蛋白抗体 liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon. Post-translational modifications: Phosphorylated at Thr-135 by CDK5 in response to osmotic stress; this phosphorylation mediates its rapid nuclear localization. Similarity: Contains 1 RHD (Rel-like) domain. Database links: Entrez Gene: 10725 Human Entrez Gene: 54446 Mouse Entrez Gene: 307820 Rat Omim:活化罢细胞核因子5蛋白抗体 604708 Human SwissProt: O94916 Human SwissProt: Q9WV30 Mouse Unigene: 371987 Human Unigene: 390057 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
活化罢细胞核因子5蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 转录调节因子 **细胞 t-**细胞 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid