9号染色体开放阅读框86抗体
规格:1尘驳/1尘濒
英文名: C9orf86
别名: Chromosome 9 open reading frame 86; FLJ10101; Hypothetical protein LOC55684; KIAA1984; Parf; Partner of ARF; pp8875; Putative GTP binding protein Parf; Rab like GTP binding protein 1; Rab like GTP bin
分子量: 80kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human C9orf86
交叉反应:Human, Mouse, Rat,
细胞定位:细胞核 细胞浆
9号染色体开放阅读框86抗体产物介绍:background: C9orf86 (Partner of ARF;PARF) binds p19(ARF), but not the p16(INK4A) isoform of CDKN2A. Knockdown of C9orf86 by RNA interference reduced the growth inhibitory activity of p19(ARF) and enhanced the rate of cell proliferation. Function: May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A. Subcellular Location: Cytoplasmic and Nuclear. Note=Predominantly cytoplasmic. Proposed to shuttle between cytoplasm and nucleus. Post-translational modifications:9号染色体开放阅读框86抗体 Isoform 1 is O-glycosylated, while other isoforms are not. Similarity: Belongs to the small GTPase superfamily. Rab family. Database links: Entrez Gene: 55684 Human Entrez Gene: 227624 Mouse Entrez Gene: 227624 Rat Omim:9号染色体开放阅读框86抗体 610615 Human SwissProt: Q3YEC7 Human SwissProt: Q5U3K5 Mouse Unigene: 370555 Human Unigene: 29600 Mouse Unigene: 443064 Mouse Unigene: 17709 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
9号染色体开放阅读框86抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid