6号染色体开放阅读框120抗体
规格:1尘驳/1尘濒
英文名: C6orf120
别名: bA160E12.4; Chromosome 6 open reading frame 120; Hypothetical protein LOC387263; UPF0669 protein C6orf120; CF120_HUMAN.
分子量: 21kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human C6orf120
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow,
细胞定位:分泌型蛋白
6号染色体开放阅读框120抗体产物介绍:background: Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency6号染色体开放阅读框120抗体and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf120 gene product has been provisionally designated C6orf120 pending further characterization. Function: May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes. Subcellular Location: Secreted. Note=Secreted by hepatocytes. Tissue Specificity: Mainly expressed in hepatocytes and some weak expression in germinal center cells of lymph nodes. 6号染色体开放阅读框120抗体Similarity: Belongs to the UPF0669 family. Database links: Entrez Gene: 387263 Human Entrez Gene: 67912 Mouse SwissProt: Q7Z4R8 Human SwissProt: Q9DAY5 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
6号染色体开放阅读框120抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 神经生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid