脑单胺类神经递质转运蛋白抗体
规格：1尘驳/1尘濒
英文名： VMAT2
别名： MNAT; Monoamine neurotransmitter transporter; Monoamine transporter; Slc18a2; Solute carrier family 18 (vesicular monoamine) member 2; Solute carrier family 18 member 2; SVAT; SVMT; Synaptic vesicle a
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human VMAT2(44
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
细胞定位：细胞浆 细胞膜
脑单胺类神经递质转运蛋白抗体产物介绍：background: Neurotransmission depends on the regulated exocytotic release of chemical transmitter molecules. This requires the packaging of these substances into the specialized secretory vesicles of neurons and neuroendocrine cells, a process mediated by specific vesicular transporters. The family of genes encoding the vesicular transporters of monoamines (VMAT 1 and VMAT 2) and acetylcholine (VACht) have been cloned and functionally characterized. The sequence of these integral membrane proteins predicts twelve transmembrane domains and weak homology to a class of bacterial antibiotic resistance proteins. The vesicular transport of neurotransmitter molecules has been shown to be an active ATP- and proton dependent transport mechanism. Function:脑单胺类神经递质转运蛋白抗体 Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis. Subunit: Interacts with SLC6A3. Subcellular Location: Cytoplasmic vesicle membrane. Similarity: Belongs to the major facilitator superfamily. Vesicular transporter family. Gene ID: 6571 Database links: Entrez Gene: 6571 Human Entrez Gene: 214084 Mouse Entrez Gene: 脑单胺类神经递质转运蛋白抗体25549 Rat Omim: 193001 Human SwissProt: Q05940 Human SwissProt: Q8BRU6 Mouse SwissProt: Q01827 Rat Unigene: 596992 Human Unigene: 268797 Mouse Unigene: 361919 Mouse Unigene: 9686 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脑单胺类神经递质转运蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid