线粒体核糖体蛋白厂4抗体
规格:1尘驳/1尘濒
英文名: MRPS4
别名: BRMS2; C15orf12; Chromosome 15 open reading frame 12; imp3; IMP3_HUMAN; Mitochondrial ribosomal protein S4; MRPS4; U3 small nucleolar ribonucleoprotein protein imp3; U3 snoRNP protein 3 homolog; U3 sn
分子量: 22kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human U3 small
交叉反应:Human, Mouse, Rat, Cow, Horse, Rabbit, Guinea Pig,
细胞定位:细胞核
线粒体核糖体蛋白厂4抗体产物介绍:background: Imp3, is a 184 amino acid protein that contains one S4 RNA-binding domain and is the mammalian homolog of the yeast Imp3 protein. Localized to the nucleus, Imp3 exists as a component of a heterotrimeric complex consisting of MPP10, Imp3 and Imp4 and, in this complex, plays a key role in early cleavage events during pre-18S ribosomal processing. The gene encoding Imp3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. 线粒体核糖体蛋白厂4抗体Function: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. Subunit: Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10. Interacts with MPHOSPH10. Subcellular Location: Nucleus, nucleolus. Similarity: Belongs to the ribosomal protein S4P family. Contains 1 S4 RNA-binding线粒体核糖体蛋白厂4抗体 domain. Gene ID: 55272 Database links: Entrez Gene: 55272 Human Entrez Gene: 102462 Mouse Entrez Gene: 315697 Rat Omim: 612980 Human SwissProt: Q9NV31 Human SwissProt: Q921Y2 Mouse Unigene: 513043 Human Unigene: 12864 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
线粒体核糖体蛋白厂4抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 **学 发育生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid