17号染色体开放阅读框75抗体
规格：1尘驳/1尘濒
英文名： C17orf75
别名： Njmu R1; Protein kinase Njmu R1; Protein Njmu R1; NJMU_HUMAN.
分子量： 45kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human C17orf75
交叉反应：Human, Mouse, Rat, Dog, Horse, Sheep,
细胞定位：
17号染色体开放阅读框75抗体产物介绍：background: C17orf75 is a 396 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.17号染色体开放阅读框75抗体 Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. Tissue Specificity: The molecular function and cellular component of this protein are unknown. It may have a role in spermatogenesis, is highly 17号染色体开放阅读框75抗体expressed in testis and is also expressed in fetal testis. Database links: Entrez Gene: 64149 Human SwissProt: Q7Z2H4 Human SwissProt: Q9HAS0 Human Unigene: 462754 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
17号染色体开放阅读框75抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid