溶质载体家族39成员11抗体
规格：1尘驳/1尘濒
英文名： SLC39A11
别名： C17orf26; S39AB_HUMAN; SLC39A11; Solute carrier family 39 (metal ion transporter) member 11; Solute carrier family 39 member 11; Zinc transporter ZIP11; ZIP-11; ZIP11; Zrt and Irt like protein 11; Zrt
分子量： 35kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SLC39A11
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
溶质载体家族39成员11抗体产物介绍：background: Zinc is an essential cofactor that is involved in cell growth and development, as well as in protein, nucleic acid and lipid metabolism. The transport of zinc across the cell membrane is crucial for correct enzyme and overall cell function. SLC39A11 (solute carrier family 39 (metal ion transporter), member 11), also known as ZIP11 (Zrt- and Irt-like protein 11), is a 342 amino acid multi-pass membrane protein belonging to the ZIP transporter family. Expressed as multiple alternatively spliced isoforms, SLC39A11 acts as a zinc-influx transporter and is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome 溶质载体家族39成员11抗体and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Function: May act as a zinc-influx transporter (By similarity). Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. Database links: Entrez Gene: 201266 Human Entrez Gene: 69806 Mouse Entrez Gene: 287796 Rat SwissProt: Q8N1S5 溶质载体家族39成员11抗体Human SwissProt: Q8BWY7 Mouse SwissProt: Q6P6S2 Rat Unigene: 221127 Human Unigene: 341021 Mouse Unigene: 205133 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
溶质载体家族39成员11抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 信号转导 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid