惭础笔激酶激活死亡域蛋白4颁抗体
规格：1尘驳/1尘濒
英文名： DENND4C
别名： C9orf55; C9orf55B; DEN4C_HUMAN; DENN domain-containing protein 4C; DENN/MADD domain containing 4C; DENND4C.
分子量： 187kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DENND4C
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆 细胞膜
惭础笔激酶激活死亡域蛋白4颁抗体产物介绍：background: DENND4C is a 1,673 amino acid multi-pass membrane protein. DENND4C contains a dDENN domain, DENN domain, uDENN domain and a PPR (pentatricopeptide) repeat. As a result of alternative splicing, six DENND4C isoforms exist. The gene encoding DENND4C maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Function:惭础笔激酶激活死亡域蛋白4颁抗体 Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin. Subcellular Location: Cytoplasmic vesicle membrane. Cell membrane. Cytoplasm, cytosol. Note=Associates with SLC2A4/GLUT4 storage vesicles. Post-translational modifications: Phosphorylated in response to insulin (By similarity). Similarity:惭础笔激酶激活死亡域蛋白4颁抗体 Contains 1 dDENN domain. Contains 1 DENN domain. Contains 1 PPR (pentatricopeptide) repeat. Contains 1 uDENN domain. Database links: Entrez Gene: 55667 Human SwissProt: Q5VZ89 Human Unigene: 249591 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产惭础笔激酶激活死亡域蛋白4颁抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid