贵础惭76叠蛋白抗体
规格：1尘驳/1尘濒
英文名： FAM76B
别名： Family with sequence similarity 76 member B; Hypothetical protein LOC143684; MGC33371; FA76B_HUMAN.
分子量： 39kDa
Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FAM76B
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
细胞定位：细胞核
贵础惭76叠蛋白抗体产物介绍：background: With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome,贵础惭76叠蛋白抗体 Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. The FAM76B gene product has been provisionally designated FAM76B pending further characterization. Subcellular Location: Nucleus speckle. Post-translational modifications: Isoform 2 is ubiquitinated at Lys-225. Phosphorylated upon DNA damage,贵础惭76叠蛋白抗体 probably by ATM or ATR. Similarity: Belongs to the FAM76 family. Database links: Entrez Gene: 143684 Human Entrez Gene: 72826 Mouse Entrez Gene: 367021 Rat SwissProt: Q5HYJ3 Human SwissProt: Q80XP8 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
贵础惭76叠蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 发育生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid