突触核膜蛋白4抗体
规格：1尘驳/1尘濒
英文名： C19orf46
别名： Nesprin-4; Nesprin4; Nesprin 4; Chromosome 19 open reading frame 46; FLJ36445; Hypothetical protein LOC163183; SYNE4_HUMAN.
分子量： 44kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human C19orf46
交叉反应：Human, Mouse, Rat, Horse, Rabbit,
细胞定位：细胞核 细胞膜
突触核膜蛋白4抗体产物介绍：background: C19orf46 is a 404 amino acid single-pass type IV membrane protein that belongs to the nesprin family. C19orf46 partcipates in the establishment of secretory epithelial morphology by inducing kinesin-dependent apical migration of the centrosome and Golgi apparatus as well as basal localization of the nucleus. C19orf46 interacts with UKHC and KCL1, and exists as two alternatively spliced isoforms. C19orf46 contains a KASH domain, which consists of a transmembrane motif, mediates nuclear enevelop targeting and binds to the SUN domain of SUN1 and SUN2. C19orf46 is encoded by a gene located on human chromosome 19, which consists of突触核膜蛋白4抗体 approximately 63 million bases and makes up over 2% of human genomic DNA. Function: Contributes to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus (By similarity). Subunit: Interacts with KIF5B and KCL1. Subcellular Location: Nucleus membrane; Single-pass type IV membrane protein Similarity: Belongs to the nesprin family. Contains 1 KASH domain. Gene ID: 163183 Database links: Entrez Gene: 163183 Human SwissProt: 突触核膜蛋白4抗体Q8N205 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
突触核膜蛋白4抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid