脂肪细胞分化因子24抗体
规格：1尘驳/1尘濒
英文名： FAD24/NOC3L
别名： C10orf117; FAD24; AD24; Factor for adipocyte differentiation 24; NOC3 like protein; NOC3 protein homolog; NOC3-like protein; noc3l; NOC3L_HUMAN; Nucleolar complex associated 3 homolog (S. cerevisiae);
分子量： 93kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NOC3L/FA
交叉反应：Human, Mouse, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
脂肪细胞分化因子24抗体产物介绍：background: GADD 153, a growth arrest and DNA damage-inducible gene, encodes a C/EBP-related nuclear protein. This protein has also been designated C/EBP-homologous protein (CHOP-10 or C/EBP zeta). GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase during cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD 153 dimers away from “classical” C/EBP binding sites, recognizing instead unique “nonclassical” sites. Thus, GADD 153 acts as a negative modulator of C/EBP-like proteins in脂肪细胞分化因子24抗体 certain terminally differentiated cells. GADD 153 belongs to the CBF/MAK21 family, which also includes NOC2L, NOC3L and NOC4L. NOC3L, also designated factor for adipocyte differentiation 24 or Fad24, promotes adipogenesis by controlling DNA replication during the early stages of mitotic clonal expansion (MCE). Function: May be required for adipogenesis. Subcellular Location: Nucleus Tissue 脂肪细胞分化因子24抗体Specificity: Expressed in colon, heart, kidney, liver, lung, placenta, skeletal muscle, small intestine, spleen and thymus. Similarity: Belongs to the CBF/MAK21 family. Gene ID: 64318 Database links: Entrez Gene: 64318 Human Omim: 610769 Human SwissProt: Q8WTT2 Human Unigene: 74899 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脂肪细胞分化因子24抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 细胞周期蛋白 细胞分化 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid