线粒体钠/氢交换蛋白质2抗体
规格：1尘驳/1尘濒
英文名： NHEDC2
别名： NHA2; Mitochondrial Na(+)/H(+) exchanger NHA2; Mitochondrial sodium/hydrogen exchanger NHA2; Na(+)/H(+) exchanger like domain containing protein 2; Na+/H+ exchanger domain containing 2; NHE domain con
分子量： 58kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NHEDC2
交叉反应：Human, Mouse, Rat, Dog, Rabbit,
细胞定位：细胞浆 细胞膜
线粒体钠/氢交换蛋白质2抗体产物介绍：background: Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms线粒体钠/氢交换蛋白质2抗体 produced by alternative splicing events. Function: Electroneutral exchange of protons for Na(+) and Li(+)across the inner mitochondrial membrane. Contributes to theorganellar volume homeostasis. Required for osteoclastdifferentiation and bone resorption activity (By similarity). Subcellular Location: Mitochondrion membrane; Multi-pass membraneprotein (By similarity). Tissue Specificity: Detected in red blood cells (at proteinlevel). Similarity: Belongs to the monovalent cation:proton antiporter 1(CPA1) transporter (TC 2.A.36) family. Database links: Entrez Gene: 133308 Human Entrez Gene: 97086 Mouse Entrez Gene: 365946 Rat Omim: 611789 Human SwissProt: Q86UD5 Human SwissProt: Q5BKR2线粒体钠/氢交换蛋白质2抗体 Mouse Unigene: 546482 Human Unigene: 441764 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
线粒体钠/氢交换蛋白质2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞周期蛋白 细胞分化 细胞骨架 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid