微管相关蛋白样蛋白3抗体
规格：1尘驳/1尘濒
英文名： EML3
别名： Echinoderm microtubule associated protein like 3; ELP 95; EMAP 3; EMAP3; EMAP-3; EML 3; EML3; EML-3; FLJ 35827; MGC 111422; EMAL3_HUMAN.
分子量： 95kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from hu EML3
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞浆
微管相关蛋白样蛋白3抗体产物介绍：background: At the onset of mitosis, assembly of the mitotic spindle requires a global change in the activity of microtubule-binding proteins. EML3 (Echinoderm microtubule-associated protein-like 3) is a 896 amino acid protein that likely modifies microtubule dynamics by making them longer. Through colocalization with spindle microtubules during mitosis, EML3 plays a role in correct metaphase chromosome alignment. EML3 contains a nuclear localization signal and a microtubule-binding domain. The gene encoding EML3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen 微管相关蛋白样蛋白3抗体syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. Function: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity). Subcellular Location: Cytoplasmic Similarity: Belongs to the 微管相关蛋白样蛋白3抗体WD repeat EMAP family. Contains 9 WD repeats. Database links: Entrez Gene: 256364 Human Entrez Gene: 225898 Mouse Entrez Gene: 293723 Rat SwissProt: Q32P44 Human SwissProt: Q8VC03 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
微管相关蛋白样蛋白3抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白 细胞分化 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid