碍叠笔蛋白抗体
规格：1尘驳/1尘濒
英文名： KBP
别名： Hypothetical protein LOC26128; KBP; KBP_HUMAN; KIAA1279; KIF1-binding protein; TTC20; Uncharacterized protein KIAA1279.
分子量： 72kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KBP
交叉反应：Human, Mouse, Rat, Horse,
细胞定位：细胞浆
碍叠笔蛋白抗体产物介绍：background: Chromosome 10 contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious. The KIAA1279 gene product has been provisionally designated KIAA1279 pending further characterization. Function: Required for organization of axonal microtubules, andaxonal outgrowth and maintenance during peripheral and centralnervous system development. 碍叠笔蛋白抗体Regulates mitochondrial transport bymodulating KIF1B motor activity. Subunit: Interacts with KIF1B. Subcellular Location: Mitochondrion. Tissue Specificity: Highly expressed in heart, brain, ovary, testis, spinal cord and all specific brain regions examined. Moderate expressed at intermediate level in all other tissues examined, as well as in fetal liver and brain. Not expressed in blood leukocytes. DISEASE: Defects in KIAA1279 are the cause of Goldberg-Shprintzenmegacolon syndrome (GOSHS) [MIM:609460]. GOSHS is characterized bymicrocephaly, mental retardation and facial dysmorphism, as well asphenotypes related to Hirschsprung disease syndrome. Similarity: Belongs to the KIF1-binding protein family. Gene 碍叠笔蛋白抗体ID: 26128 Database links: Entrez Gene: 100063227 Horse Entrez Gene: 26128 Human Entrez Gene: 72320 Mouse Entrez Gene: 606294 Rat Omim: 609367 Human SwissProt: Q96EK5 Human SwissProt: Q6ZPU9 Mouse SwissProt: Q4G074 Rat Unigene: 279580 Human Unigene: 258955 Mouse Unigene: 100975 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
碍叠笔蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 细胞周期蛋白 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid