艾滋病病毒辫55/辫17抗体
规格：1尘驳/1尘濒
英文名： HIV1 p55 + p17
别名： HIV1 p17; HIV1 p55; Gag; Gag polyprotein; Pr55; Pr55Gag; HIV1 Pr55Gag; Human immunodeficiency virus 1 p55; HIV1 p55+p17; HIV1 matrix protein p17; MA; Matrix protein; Matrix protein p17; Human immunode
分子量： 17/55kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from HIV1 p55/p17
交叉反应：贬滨痴
细胞定位：细胞浆 细胞膜
艾滋病病毒辫55/辫17抗体产物介绍：background: HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. p55 is digested by HIV1 protease into intermediate products p41 and p15. p41 is further digested into matrix protein p17 and capsid protein p24. Likewise, p15 is further digested into nucleocapsid protein p7 and to p6 and p1. Subunit: Matrix protein p17, and probably Pr55Gag form hexamer rings of trimers. Oligomerization possibly creates a central hole into which the cytoplasmic tail艾滋病病毒辫55/辫17抗体 of the gp41 envelope protein may be inserted. Pr55Gag interacts with host TRIM22; this interaction seems to disrupt proper trafficking of Gag polyprotein and may interfere with budding. p6-gag interacts with Vpr. p6-gag interacts with host TSG101. p6-gag interacts with host PDCD6IP/AIP1 (By similarity). Pr55Gag interacts with host PDZD8. Subcellular Location: Matrix protein p17: Virion (Potential). Host nucleus (By similarity). Host cytoplasm (By similarity). Host cell membrane; Lipid-anchor (Potential). Note=Following virus entry, the nuclear localization signal (NLS) 艾滋病病毒辫55/辫17抗体of the matrix protein participates with Vpr to the nuclear localization of the viral genome. During virus production, the nuclear export activity of the matrix protein counteracts the NLS to maintain the Gag and Gag-Pol polyproteins in the cytoplasm, thereby directing unspliced RNA to the plasma membrane. Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Similarity: Belongs to the primate lentivirus group gag polyprotein family. Contains 2 CCHC-type zinc fingers. Gene ID: 155030 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产艾滋病病毒辫55/辫17抗体品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 **及病毒
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid