3号染色体开放阅读框39抗体
规格：1尘驳/1尘濒
英文名： C3orf39
别名： AGO61; Chromosome 3 open reading frame 39; FLJ14566; Uncharacterized glycosyltransferase AGO61 precursor; GTDC2_HUMAN.
分子量： 65kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human C3orf39
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
细胞定位：分泌型蛋白
3号染色体开放阅读框39抗体产物介绍：background: C3orf39, also known as AGO61, is a 580 amino acid secreted protein belonging to the glycosyltransferase 61 family. C3orf39 is encoded by a gene that maps to human chromosome 3p25.1. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3. Subcellular Location: Secreted (Potential). Tissue Specificity: Highly expressed in the brain, 3号染色体开放阅读框39抗体muscle, heart, and kidney in both fetus and . In the brain, highest expression in the cortex and cerebellum. Highly expressed in the pancreas. DISEASE: Defects in GTDC2 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A8 (MDDGA8) [MIM:614830]. An autosomal recessive disorder characterized by congenital muscular dystrophy associated with 3号染色体开放阅读框39抗体cobblestone lissencephaly and other brain anomalies, eye malformations, profound mental retardation, and death usually in the first years of life. Included diseases are the more severe Walker-Warburg syndrome and the slightly less severe muscle-eye-brain disease. Similarity: Belongs to the glycosyltransferase 61 family. Gene ID: 84892 Database links: Entrez Gene: 84892 Human SwissProt: Q8NAT1 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
3号染色体开放阅读框39抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 IEM=1:20-200 IGS=1:20-200 GICA=1:20-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid