胸腺素β4抗体
规格：1尘驳/1尘濒
英文名： Thymosin beta 4
别名： Tβ4; FX; Hematopoietic system regulatory peptide; Prothymosin beta 4; PTMB 4; PTMB4; Seraspenide; T beta 4; T beta-4; TB4X; THYB 4; Thyb4; Thymosin beta 4; Thymosin beta 4 X chromosome; Thymosin beta
分子量： 4.8kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Thymosin
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
胸腺素β4抗体品介绍：background: Proteins in the thymosin beta family are highly conserved polar peptides that bind monomeric Actin and thereby inhibit Actin polymerization. These proteins act as the main intracellular G-Actin sequestering peptides. The most abundant thymosin beta family member in mammalian cells and tissues is thymosin beta-4 (Tbeta-4), also designated Seraspenide. T beta-4 participates in several cellular events including cancerogenesis, apoptosis, angiogenesis, blood coagulation and would healing. Specifically, T beta-4 promotes cell migration and adhesion, accelerates wound healing and reduces inflammation, and becomes upregulated in a wide variety of human carcinomas. Due to the effects of T beta-4 in these events, it may become a protein of significant biological and pharmaceutical relevance.胸腺素β4抗体 Function: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase. Subcellular Location: Cytoplasm, cytoskeleton. Tissue Specificity: Originally found in thymus but it is widely distributed in many tissues. Similarity: Belongs to the thymosin beta family. Gene ID: 7114 Database links: Entrez Gene: 7114 Human Entrez Gene: 19241 Mouse Entrez Gene: 81814 Rat Omim: 300159 Human 胸腺素β4抗体SwissProt: P62327 Horse SwissProt: P62328 Human SwissProt: P20065 Mouse SwissProt: P62329 Rat SwissProt: Q0P5V6 Rat Unigene: 437277 Human Unigene: 142729 Mouse Unigene: 409203 Mouse Unigene: 168067 Rat Unigene: 2605 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Tβ-4.
胸腺素β4抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 信号转导 细胞骨架 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid