血小板衍化生长因子γ抗体
规格：1尘驳/1尘濒
英文名： PAFAHG
别名： PA1B3_HUMAN; PAF acetylhydrolase 29 kDa subunit; PAF AH 29 kDa subunit; PAF AH subunit gamma; PAF-AH 29 kDa subunit; PAF-AH subunit gamma; PAFAH subunit gamma; Pafah1b3; PAFAHG; Platelet activating fa
分子量： 26kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PAFAH1B3
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
血小板衍化生长因子γ抗体产物介绍：background: The platelet activating factor (PAF) acetylhydrolases catalyze hydrolysis of the sn-2 ester bond of PAF and related pro-inflammatory phospholipids and thus attenuate their bioactivity. The family of PAF acetylhydrolases includes one secreted plasma isozyme and two intracellular isozymes. The intracellular isozymes are distinguished by differences in their primary sequence, tissue localization, subunit composition and substrate preferences. The most thoroughly characterized intracellular isoform, PAFAH1B, is a heterotrimeric protein expressed in brain tissue and plays and important role in brain development and function. PAFAH1B is comprised of a regulatory subunit (LIS1) and two homologous (63% identity) catalytic subunits (PAFAH1B2 and PAFAH1B3), which harbor all the activity of the enzyme. The PAFAH1B2 and PAFAH1B3 subunits readily associate with very high affinity to form heterodimers, and this dimerization is essential for both stability and catalytic activity. PAFAH1B3 is also commonly known as PAFAH1B 29kDa subunit, PAFAH1B subunit or PAFAH1B subunit α1. Function: Inactivates paf by removing the acetyl group at the sn-2position. This is a catalytic subunit. Plays an important roleduring the development of brain. Subunit:血小板衍化生长因子γ抗体 Cytosolic PAF-AH IB is formed of three subunits of 45 kDa(alpha), 30 kDa (beta) and 29 kDa (gamma). The catalytic activityof the enzyme resides in the beta and gamma subunits, whereas thealpha subunit has regulatory activity. Trimer formation is notessential for the catalytic activity. Subcellular Location: Cytoplasm. Tissue Specificity: In the , expressed in brain, skeletal muscle, kidney, thymus, spleen, colon, testis, ovary and peripheral blood leukocytes. In the fetus, highest expression occurs in brain. Similarity: Belongs to the 'GDSL' lipolytic enzyme family.Platelet-activating factor acetylhydrolase IB beta/gamma subunitssubfamily. Database links: Entrez Gene: 5050 Human Entrez Gene: 血小板衍化生长因子γ抗体18476 Mouse Entrez Gene: 114113 Rat Omim: 603074 Human SwissProt: Q15102 Human SwissProt: Q61205 Mouse SwissProt: O35263 Rat Unigene: 466831 Human Unigene: 597 Mouse Unigene: 17971 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血小板衍化生长因子γ抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid