血小板衍化生长因子β抗体
规格：1尘驳/1尘濒
英文名： PAFAH1B2
别名： PA1B2_HUMAN; PAF acetylhydrolase 30 kDa subunit; PAF AH 30 kDa subunit; PAF AH beta subunit; PAF AH subunit beta; PAF-AH 30 kDa subunit; PAF-AH subunit beta; PAFAH 30 kDa subunit; PAFAH beta subunit;
分子量： 25kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PAFAH1B2
交叉反应：Human, Mouse, Rat, Horse, Sheep,
细胞定位：细胞浆
血小板衍化生长因子β抗体产物介绍：background: PAFAH1B2, also known as PAFAHB, is a 229 amino acid cytoplasmic protein that belongs to the GDSL lipolytic enzyme family and the platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily. A ubiquitously expressed catalytic subunit of the cytosolic PAFAH1B heterotrimeric complex, PAFAH1B2 inactivates PAF by removing the acetyl group at the sn-2 position. Along with the beta subunit, PAFAH1B is made up of alpha and gamma subunits. The gene that encodes PAFAH1B2 consists of approximately 32,628 bases and maps to human chromosome 11q23.3. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11. Function: Inactivates PAF by removing the acetyl group at the sn-2position.血小板衍化生长因子β抗体 This is a catalytic subunit. Subunit: Cytosolic PAF-AH IB is formed of three subunits of 45 kDa(alpha), 30 kDa (beta) and 29 kDa (gamma). The catalytic activityof the enzyme resides in the beta and gamma subunits, whereas thealpha subunit has regulatory activity. Trimer formation is notessential for the catalytic activity. Subcellular Location: Cytoplasm. Tissue Specificity: Ubiquitous. Similarity: Belongs to the 'GDSL' lipolytic enzyme family.Platelet-activating factor acetylhydrolase IB beta/gamma subunitssubfamily. Database links: Entrez Gene: 血小板衍化生长因子β抗体5049 Human Entrez Gene: 18475 Mouse Entrez Gene: 64189 Rat Omim: 602508 Human SwissProt: P68402 Human SwissProt: Q61206 Mouse SwissProt: O35264 Rat Unigene: 597488 Human Unigene: 200859 Mouse Unigene: 24751 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血小板衍化生长因子β抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid