血红素结合蛋白1抗体
规格：1尘驳/1尘濒
英文名： HEBP1
别名： HBP; HEBP; Hebp1; HEBP1_HUMAN; Heme binding protein 1; Heme-binding protein 1; p22HBP.
分子量： 21kD
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HEBP1/p2
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
细胞定位：细胞浆
血红素结合蛋白1抗体产物介绍：background: p22HBP, also known as HEBP1 (heme binding protein 1), HBP or HEBP, is a 189 amino acid intracellular tetrapyrrole-binding protein that assists in prevention of cellular toxicity by removing free porphyrinogens from the cell. Existing as a monomer, p22HBP localizes to cytoplasm and contains a 21 amino acid chemoattractant within its N-terminus that functions as a natural ligand for FPR3. p22HBP is a member of the HEBP family and binds N-methylprotoporphyrin and metalloporphyrins with similar affinity to porphyrinogens. The gene encoding p22HBP maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders. Function: May bind free血红素结合蛋白1抗体 porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities. Subunit: Monomer. Subcellular Location: Cytoplasm. Tissue Specificity: May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities. Similarity: Belongs to the HEBP family. Database links: Entrez Gene: 50865 Human Entrez 血红素结合蛋白1抗体Gene: 15199 Mouse Entrez Gene: 362454 Rat Omim: 605826 Human SwissProt: Q9NRV9 Human SwissProt: Q9R257 Mouse Unigene: 642618 Human Unigene: 378937 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血红素结合蛋白1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 信号转导 结合蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid