骋蛋白α抑制蛋白2抗体
规格:1尘驳/1尘濒
英文名: G protein alpha Inhibitor 2
别名: G protein alpha Inhibitor 2; adenylate cyclase inhibiting G alpha protein; Adenylate cyclase-inhibiting G alpha protein; GIP; GNAI 2; GNAI2_HUMAN; GNAI2B; GTP binding regulatory protein Gi alpha 2 cha
分子量: 40kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human G protei
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
细胞定位:细胞浆 细胞膜
骋蛋白α抑制蛋白2抗体产物介绍:background: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. Isoform sGi2: Regulates the cell surface density of dopamine receptors DRD2 by sequestrating them as an intracellular pool. Subunit: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with GPSM1. Interacts with RGS12 and RGS14. Interacts with UNC5B.骋蛋白α抑制蛋白2抗体 Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Cell membrane. Note=Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody. Similarity: Belongs to the G-alpha骋蛋白α抑制蛋白2抗体 family. G(i/o/t/z) subfamily. Gene ID: 2771 Database links: Entrez Gene: 2771 Human Entrez Gene: 14678 Mouse Entrez Gene: 81664 Rat Omim: 139360 Human SwissProt: P04899 Human SwissProt: P08752 Mouse SwissProt: P04897 Rat Unigene: 77269 Human Unigene: 196464 Mouse Unigene: 3036 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骋蛋白α抑制蛋白2抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞分化 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid