贰1础激活基因刺激蛋白2抗体
规格:1尘驳/1尘濒
英文名: CREG2
别名: CREG 2; CREG-2; Cellular repressor of E1A stimulated genes 2; CREG2_HUMAN.
分子量: 29kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CREG2
交叉反应:Human, Mouse, Rat,
细胞定位:
贰1础激活基因刺激蛋白2抗体产物介绍:background: The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. CREG (cellular repressor of E1A-stimulated genes) is a cellular protein that antagonizes transcriptional activation and cellular transformation by E1A. CREG was initially isolated in a yeast two-hybrid screen due to its interaction with the TATA-binding protein, TBP. A member of the CREG family, CREG2 (cellular repressor of E1A-stimulated genes 2) is a novel protein that shares 35% homology with CREG and is expressed at highest levels in brain. CREG2 is a secreted protein containing 290 amino acids whose N-terminus贰1础激活基因刺激蛋白2抗体 is thought to function as a signal sequence. The gene encoding CREG2 maps to human chromosome 2, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases贰1础激活基因刺激蛋白2抗体 are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome. Subunit: Secreted. Tissue Specificity: Brain specific mainly in the limbic system and faintly in the spinal cord but not in cerebellum. Post-translational modifications: It is not sure whether N-glycosylation is on Asn-165 and/or Asn-166. Similarity: Belongs to the CREG family. Database links: UniProtKB/Swiss-Prot: Q8IUH2.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
贰1础激活基因刺激蛋白2抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid