磷酸二酯酶1颁抗体
规格:1尘驳/1尘濒
英文名: PDE1C
别名: 5''-cyclic nucleotide phosphodiesterase 1C; Calcium/calmodulin dependent 3'5' cyclic nucleotide phosphodiesterase 1C; Calcium/calmodulin-dependent 3''; Cam PDE 1C; Cam-PDE 1C; hCam 3; hCam-3; HCAM3; H
分子量: 81kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PDE1C
交叉反应:Human, Mouse, Rat, Rabbit,
细胞定位:细胞浆
磷酸二酯酶1颁抗体产物介绍:background: Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM, Oct 2009] Function: 磷酸二酯酶1颁抗体Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in several tissues, including brain and heart. Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily. Database links: Entrez Gene: 5137 Human Entrez Gene: 18575 Mouse Entrez Gene: 81742 Rat Omim: 602987 Human SwissProt: Q14123 Human SwissProt: Q64338 Mouse 磷酸二酯酶1颁抗体SwissProt: Q63421 Rat Unigene: 728862 Human Unigene: 5145 Mouse Unigene: 10289 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸二酯酶1颁抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 染色质和核信号 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid