4号染色体开放阅读框14抗体
规格：1尘驳/1尘濒
英文名： C4orf14
别名： mAtNOS1; Chromosome 4 open reading frame 14; hAtNOS1; Hypothetical protein LOC84273; MGC3232; Putative ortholog of Arabidopsis mitochondrial nitric oxide synthase; Uncharacterized protein C4orf14; NOA
分子量： 78kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human C4orf14
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆 细胞膜
4号染色体开放阅读框14抗体产物介绍：background: Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of 4号染色体开放阅读框14抗体the two lowest recombination frequencies of the human chromosomes. The C4orf14 gene product has been provisionally designated C4orf14 pending further characterization. Function: Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes.4号染色体开放阅读框14抗体 Binds GTP. Subunit: Homodimer or multimer (By similarity). Interacts with mitochondrial complex I, DAP3, MRPL12 and MRPS27. Subcellular Location: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Similarity: Belongs to the NOA1 family. Database links: Entrez Gene: 84273 Human SwissProt: Q8NC60 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
4号染色体开放阅读框14抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 发育生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid