转录延伸调节蛋白1抗体
规格:1尘驳/1尘濒
英文名: TCERG1
别名: CA 150; Co activator of 150 kDa; Coactivator of 150 kDa; MGC133200; TAF 2S; TAF2S; TATA box binding protein (TBP) associated factor RNA polymerase II S 150kD; TATA box binding protein associated facto
分子量: 124kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TCERG1/C
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞核
转录延伸调节蛋白1抗体产物介绍:background: CA150 is a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. It interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Function: Transcription factor that binds RNA polymerase II and inhibits the 转录延伸调节蛋白1抗体elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter. Subunit: Binds formin (By similarity). Binds RNA polymerase II, HD and SF1. Subcellular Location: Nucleus. Tissue Specificity: Detected in brain neurons. Similarity:转录延伸调节蛋白1抗体 Contains 6 FF domains. Database links: UniProtKB/Swiss-Prot: O14776.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录延伸调节蛋白1抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 转录调节因子 肿瘤细胞生物标志物 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid