转录因子础笔-2γ抗体
规格：1尘驳/1尘濒
英文名： AP2 gamma
别名： TFAP2C; AP2 γ; Activating enhancer binding protein 2 gamma; Activating enhancer-binding protein 2 gamma; AP2-gamma; AP2C_HUMAN; AP2g; AP2gamma; ERF 1; ERF1v; Estrogen receptor factor 1; hAP 2g; hAP2g;
分子量： 49kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TFAP2C (
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit,
细胞定位：细胞核
转录因子础笔-2γ抗体产物介绍：background: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Function: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube 转录因子础笔-2γ抗体development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Subunit: Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members (By similarity). Interacts with WWOX. Interacts with CITED4.转录因子础笔-2γ抗体Interacts with UBE2I. Interacts with KCTD1; this interaction represses transcription activation. Interacts with CITED2 (via C-terminus); the vinteraction stimulates TFAP2B-transcriptional activity. Subcellular Location: Nucleus. Post-translational modifications: Sumoylated on Lys-10; which inhibits transcriptional activity. Similarity: Belongs to the AP-2 family. Database links: UniProtKB/Swiss-Prot: Q92754.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子础笔-2γ抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞周期蛋白 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid