周期素叠2抗体
规格:1尘驳/1尘濒
英文名: Cyclin B2
别名: Cyclin-B2; CycB2; G2 mitotic specific cyclin B2; G2/mitotic specific cyclin B2; CCNB2_HUMAN.
分子量: 45kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Cyclin B
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:
周期素叠2抗体产物介绍:background: Cyclin B2 belongs to a the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin B2 has been shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other周期素叠2抗体 in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Function: Essential for the control of the cell cycle at the G2/M 周期素叠2抗体(mitosis) transition. Subunit: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex. Similarity: Belongs to the cyclin family. Cyclin AB subfamily. Database links: UniProtKB/Swiss-Prot: O95067.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
周期素叠2抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 细胞周期蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid