促肾上腺皮质释放**受体2抗体
规格：1尘驳/1尘濒
英文名： CRHR2
别名： Corticotropin releasing hormone receptor 2; Corticotropin-releasing factor receptor 2; Corticotropin-releasing hormone receptor 2; CRF 2; CRF 2R; CRF R2; CRF-R-2; CRF-R2; CRF2; CRF2R; CRFR 2; CRFR-2;
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CRHR2
交叉反应：Human, Mouse, Rat, Chicken, Pig, Horse,
细胞定位：细胞膜
促肾上腺皮质释放**受体2抗体产物介绍：background: The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011] Function: This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. Also binds to urocortin 促肾上腺皮质释放**受体2抗体I, II and III. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Subunit: Interacts (via N-terminal extracellular domain) with CRF, UCN, UCN2 and UCN3. Has highest affinity for UCN, and considerably lower affinity for CRF, UNC2 and UCN3. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 2促肾上腺皮质释放**受体2抗体 family. Gene ID: 1395 Database links: Entrez Gene: 1395 Human Entrez Gene: 12922 Mouse Entrez Gene: 64680 Rat Omim: 602034 Human SwissProt: Q13324 Human SwissProt: Q60748 Mouse SwissProt: P47866 Rat Unigene: 546246 Human Unigene: 236081 Mouse Unigene: 10023 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
促肾上腺皮质释放**受体2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 G蛋白偶联受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid