骋蛋白偶联受体惭搁骋齿1抗体
规格：1尘驳/1尘濒
英文名： MRGX1
别名： MRGPRC; G protein coupled receptor MRGX1; G protein coupled receptor SNSR3; GPCR; Mas related G protein coupled receptor member X1; MAS related gene MRGX1; MAS related GPR member X1; MRGPRX1; MRGX1; S
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MRGX1
交叉反应：贬耻尘补苍,
细胞定位：细胞膜
骋蛋白偶联受体惭搁骋齿1抗体产物介绍：background: Mas-related G protein-coupled receptor member X1 (MRGX) is a sensory neuron-specific G protein-coupled receptor that is involved in the function of nociceptive neurons. This integral membrane protein may also regulate nociceptor development and/or the sensation or modulation of pain. There are four members (MRGX1-4) in the human MRGX familly. MRGX1 and MRGX2 receptors stimulate both G Alpha q- and G Alpha i -regulated pathways, while MRGX3 and MRGX4 receptors mainly activate G Alpha q-regulated pathways. G Alpha q proteins are involved in the calcium-signaling pathway downstream of the MRGX receptors. MRGX receptors are unique in that they are expressed in a subset of small dorsal root and trigeminal sensory neurons. Function: MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor 骋蛋白偶联受体惭搁骋齿1抗体function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. Subcellular Location: Cell Membrane; Multi-pass membrane protein. Tissue Specificity:骋蛋白偶联受体惭搁骋齿1抗体 Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. Similarity: Belongs to the G-protein coupled receptor 1 family. Mas subfamily. Database links: UniProtKB/Swiss-Prot: Q96LB2.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骋蛋白偶联受体惭搁骋齿1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子 G蛋白偶联受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid