脱氧尿苷叁磷酸酶顿鲍罢抗体
规格：1尘驳/1尘濒
英文名： DUT
别名： DUT-N; mitochondrial; Deoxyuridine 5' triphosphate nucleotidohydrolase, nuclear isofor; Deoxyuridine 5''-triphosphate nucleotidohydrolase; Deoxyuridine triphosphatase; dut; DUT_HUMAN; dUTP nucleotidoh
分子量： 19kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DUT (191
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞核 细胞浆
脱氧尿苷叁磷酸酶顿鲍罢抗体产物介绍：background: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. Function: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. Subunit: Homotrimer. Subcellular Location: Isoform 2: Nucleus. Isoform 3: Mitochondrion. Tissue Specificity: Found in a variety of tissues. Isoform 3 expression is constitutive, while isoform 脱氧尿苷叁磷酸酶顿鲍罢抗体2 expression correlates with the onset of DNA replication (at protein level). Isoform 2 degradation coincides with the cessation of nuclear DNA replication (at protein level). Post-translational modifications: Nuclear isoform 2 is phosphorylated in vivo on Ser-11, a reaction that can be catalyzed in vitro by CDC2. Phosphorylation in mature T-cells occurs in a cell cycle-dependent manner. Isoform脱氧尿苷叁磷酸酶顿鲍罢抗体 3 is not phosphorylated. The initiator methionine is cleaved in isoform 2. Similarity: Belongs to the dUTPase family. Database links: UniProtKB/Swiss-Prot: P33316.4 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
脱氧尿苷叁磷酸酶顿鲍罢抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 染色质和核信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid