核仁蛋白8抗体
规格:1尘驳/1尘濒
英文名: NOL8
别名: C9orf34; NOL8; NOL8_HUMAN; NOP132; Nucleolar protein 8; Nucleolar protein Nop132.
分子量: 132kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NOL8 (84
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞核
核仁蛋白8抗体产物介绍:background: Summary: NOL8 binds Ras-related GTP-binding proteins (see MIM 608267) and plays a role in cell growth Function: Plays an essential role in the survival of diffuse-type gastric cancer cells. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells. Subunit: Interacts with the GTP form of RRAGA, RRAGC and RRAGD. Interacts with NIP7. Interacts with DDX18; the interaction is RNA-dependent. Interacts with DDX47; the 核仁蛋白8抗体interaction is RNA-dependent. Subcellular Location: Nucleus, nucleolus. Note=Localizes in the nucleolar-organizing region during ribosome biogenesis. Tissue Specificity: Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle. 核仁蛋白8抗体Post-translational modifications: Phosphorylated Similarity: Contains 1 RRM (RNA recognition motif) domain. Database links: UniProtKB/Swiss-Prot: Q76FK4.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核仁蛋白8抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 肿瘤细胞生物标志物 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid