干细胞转录因子狈础狈翱骋笔8抗体
规格:1尘驳/1尘濒
英文名: NANOGP8
别名: Homeobox protein NANOGP8; MGC119250; NANOG; Nanog homeobox pseudogene 8; NANOGP 8; NANOGP1; NANOGP8; NANP8_HUMAN.
分子量: 34kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NANOGP8
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞核
干细胞转录因子狈础狈翱骋笔8抗体产物介绍:background: This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein 干细胞转录因子狈础狈翱骋笔8抗体have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009] Function: May act as a transcription regulator. When overexpressed, promotes entry of cells into S phase and cell proliferation. Subcellular Location: Nucleus. Tissue Specificity: Expressed in osteosarcoma cancer cell line (at protein level). breast and urinary bladder 干细胞转录因子狈础狈翱骋笔8抗体tissues, and also osteosarcoma, hepatoma, and breast adenocarcinoma cancer cell lines. Similarity: Belongs to the Nanog homeobox family. Contains 1 homeobox DNA-binding domain. Gene ID: 388112 Database links: Entrez Gene: 388112 Human SwissProt: Q6NSW7 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
干细胞转录因子狈础狈翱骋笔8抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 染色质和核信号 转录调节因子 肿瘤细胞生物标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid