惭驰颁诱导线粒体蛋白抗体
规格:1尘驳/1尘濒
英文名: Mimitin
别名: mitochondrial; B17.2 like; B17.2-like; B17.2L; MIMIT_HUMAN; Mimitin; Mimitin mitochondrial; MMTN; Myc induced mitochondrial protein; Myc-induced mitochondrial protein; NADH dehydrogenase (ubiquinone)
分子量: 20kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Mimitin
交叉反应:Human, Mouse, Rat,
细胞定位:
惭驰颁诱导线粒体蛋白抗体产物介绍:background: NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene cause progressive encephalopathy resulting from mitochondrial complex I deficiency. Function: Acts as a molecular chaperone for mitochondrial complex I assembly. Subunit: Mitochondrion. Subcellular Location: Highly expressed in ESCC cells. Also expressed in heart, skeletal muscle, liver, and in fibroblasts. 惭驰颁诱导线粒体蛋白抗体DISEASE: Defects in NDUFAF2 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to -onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver 惭驰颁诱导线粒体蛋白抗体disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. Similarity: Belongs to the complex I NDUFA12 subunit family. Database links: UniProtKB/Swiss-Prot: Q8N183.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产惭驰颁诱导线粒体蛋白抗体品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 信号转导 肿瘤细胞生物标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid