细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体
规格：1尘驳/1尘濒
英文名： FOLH1B
别名： PSMAL; Cell growth inhibiting gene 26 protein; Folate hydrolase 1B; Folate hydrolase 2; Folate hydrolase pseudogene; FOLH2; FOLHP; GCP3; GCPIII; glutamate carboxypeptidase III; N acetylated alpha link
分子量： 50kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FOLH1B (
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞浆
细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体产物介绍：background: Prostate cancer is the most frequently diagnosed cancer and the early detection of prostate cancer dramatically and efficiently reduces the observed mortality rate. Several proteins have been identified as specific markers of prostate cancer, and they may be useful as diagnostic indicators. PSA, prostate specific antigen, is the classical indicator for transformed prostate tissue; however, in addition to being upregulated in prostate cancer, PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia prostate. Conversely, STEAP (six-transmembrane epithelial antigen of the prostate), prostate carcinoma tumor antigen (PCTA-1) and prostate-specific membrane antigen (PSM) represent additional prostate-specific antigens that are overexpressed only in malignant tumors and therefore are more specific identifiers of malignancies. PSM is an integral membrane protein, and PCTA-1 is related to the galectin gene family, which mediate both cell-cell and cell-matrix interactions in a manner similar to the selectin subgroup of C-type lectins. STEAP is a serpentine transmembrane cell-surface tumor-antigen that is predicted to functions as a channel or transporter protein. In addition to prostate cancers, 细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体STEAP is also upregulated in bladder, colon and ovarian cancers. Function: Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Exhibits a dipeptidyl-peptidase IV type activity. Subcellular Location: Cytoplasm Tissue Specificity: Kidney and liver. Not expressed in the prostate. Similarity: Belongs to the peptidase M28 family. M28B subfamily. Database links: Entrez Gene: 219595 Human Omim: 609020 Human SwissProt: Q9HBA9 Human Unigene: 645352 Human Important Note:细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞生长抑制蛋白26/前列腺特异性膜抗原样蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 信号转导 肿瘤细胞生物标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid