环指蛋白45/自分泌运动因子受体抗体
规格：1尘驳/1尘濒
英文名： RNF45
别名： AMF receptor; AMF receptor isoform 1; AMF receptor isoform 2; AMFR; AMFR2_HUMAN; Autocrine motility factor receptor; Autocrine motility factor receptor precursor, isoform 1; Autocrine motility factor
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human AMFR/RNF
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit,
环指蛋白45/自分泌运动因子受体抗体细胞定位：细胞浆 细胞膜
产物介绍：background: E3 ubiquitin-protein ligase which can target both itself and other proteins including CD3D and APOB for proteasomal degradation. Mediates polyubiquitination of CYP3A4. Specific receptor for the autocrine motility factor. Mediates tumor invasion and metastasis. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol. Promotes ubiquitination of misfolded proteins such as mutant CFTR; proposed to mediate sequential ubiquitination by recognizing already ubiquitin-conjugated substrates and to cooperate with E3 ubiquitin-protein环指蛋白45/自分泌运动因子受体抗体 ligase RNF5. Subcellular Location: Endoplasmic reticulum membrane. Similarity: Contains 1 CUE domain. Contains 1 RING-type zinc finger. Gene ID: 267 Database links: Entrez Gene: 267 Human Entrez Gene: 23802 Mouse环指蛋白45/自分泌运动因子受体抗体 Omim: 603243 Human SwissProt: Q9UKV5 Human SwissProt: Q9R049 Mouse Unigene: 295137 Human Unigene: 34641 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
环指蛋白45/自分泌运动因子受体抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 肿瘤细胞生物标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid