早老素γ分泌酶2抗体
规格：1尘驳/1尘濒
英文名： PEN2
别名： Gamma secretase subunit PEN 2; Gamma Secretase Subunit PEN2; Gamma-secretase subunit PEN-2; Hematopoietic stem/progenitor cells protein MDS033; MDS033; MSTP064; PEN 2; PEN-2; PEN2_HUMAN; Presenilin En
分子量： 11kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PEN2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：细胞浆 细胞膜
早老素γ分泌酶2抗体产物介绍：background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity. Subunit: Component of the gamma-secretase complex, a complex composed of a presenilin homodimer (PSEN1 or PSEN2),早老素γ分泌酶2抗体 nicastrin (NCSTN), APH1 (APH1A or APH1B) and PSENEN/PEN2. Such minimal complex is sufficient for secretase activity, although other components may exist. Subcellular Location: Endoplasmic reticulum membrane. Golgi apparatus > Golgi stack membrane. Predominantly located in the endoplasmic reticulum and in the cis-Golgi. Tissue Specificity: Widely expressed. Expressed in leukocytes, lung,早老素γ分泌酶2抗体 placenta, small intestine, liver, kidney, spleen thymus, skeletal muscle, heart and brain. Similarity: Belongs to the PEN-2 family. Database links: UniProtKB/Swiss-Prot: Q9NZ42.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产物应用：早老素γ分泌酶2抗体WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid