泌乳素受体抗体
规格：1尘驳/1尘濒
英文名： PRLR
别名： Lactogen receptor; MGC105486; OPR; Pr-1; Pr-3; PRL R; PRL-R; PRLR; Prlr-rs1; PRLR_HUMAN; Prolactin receptor a; Prolactin receptor; Prolactin receptor delta 7/11; RATPRLR; Secreted prolactin binding pr
分子量： 67kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Prolacti
交叉反应：Human, Mouse, Rat, Pig, Rabbit,
细胞定位：细胞膜 分泌型蛋白
泌乳素受体抗体产物介绍：background: This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]. Function: This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform泌乳素受体抗体 6 is unable to transduce prolactin signaling. Subunit: Homodimer upon hormone binding. Interacts with SMARCA1. Interacts with GH1. Interacts with CSH. Interacts with NEK3 and VAV2 and this interaction is prolactin-dependent. Subcellular Location: Membrane; Single-pass type I membrane protein. Isoform 7: Secreted. Tissue Specificity: Expressed in breast, placenta, kidney, liver and pancreas. Similarity: Belongs to the type I cytokine receptor family. Type 1 subfamily. Contains 2 fibronectin type-III domains. Database links: Entrez Gene: 100053793 Horse 泌乳素受体抗体Entrez Gene: 5618 Human Entrez Gene: 414916 Pig Entrez Gene: 24684 Rat Omim: 176761 Human SwissProt: P16471 Human SwissProt: Q6JTA8 Pig SwissProt: P14787 Rabbit SwissProt: P05710 Rat SwissProt: O46561 Sheep Unigene: 368587 Human Unigene: 9757 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
泌乳素受体抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 信号转导 生长因子和** 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid